National Research Project
“INAPPROPRIATE PRESCRIBING IN THE ELDERLY PATIENT “
List of investigators in charge of the units involved in the study
Achille Patrizio Caputi
The co-occurrence of multiple chronic illnesses is common in elderly people. Because of the complexity of the geriatric patient, physicians should carefully assess the benefit/risk ratio of any drug prescription. Indeed, although the potential benefits of pharmacotherapy are unquestionable, the negative outcomes of medications in older people are a relevant issue.
The definition of “Inappropriate Prescribing” (IP) in the geriatric population is still debated. Nowadays, all available IP criteria (e.g. Beers) are based on experts’ consensus, and they often lack a formal validation based on ‘hard’ end-points (e.g. hospitalization). Furthermore, IP criteria are not specifically tailored to cardiovascular diseases, which constitute the most frequent conditions affecting the elderly population.
To define a series of IP indicators among elderly patients who suffer from cardiovascular diseases and other chronic comorbidities; to evaluate the relationship between the IP and ‘hard’ end-points (one-year acute cardiovascular events, all-cause hospitalization and
Pages: 1 2